Fungicore/ Anti-infectives

Product Properties

Composition

Fluconazole 200mg

Available form

Capsule

Primary use

Anti-fungal

Prescription required

Yes

Uses
Treatment of the following conditions in adults and children

  • Cryptococcal meningitis and maintenance therapy to prevent relapse of cryptococcal disease in patients with AIDS.
  • Systemic candidiasis.
  • Oropharyngeal and oesophageal candidiasis.
  • Prevention of fungal infections in patients with malignancy who are predisposed to such infections as a result of cytotoxic chemotherapy and radiotherapy.
  • Vaginal candidiasis, acute or recurrent and prophylaxis to reduce the incidence of recurrent vaginal candidiasis
  • Candidial balanitis
  • Dermatomycosis including tinea cruris, tinea corporis, tinea pedis, tinea unguium (onychomycosis), and dermal candida infection

How it works
Fluconazole is a triazole antifungal drug which inhibits the cytochrome P-450 dependent enzymes resulting in impairment of ergosterol synthesis in the fungal cell membranes
How to use
Fungicore is taken orally in a dose adjusted manner, depending on the condition and the results of cultures and laboratory studies.
Side effects
Most commonly reported side effects include gastrointestinal symptoms such as abdominal pain, diarrhoea, nausea, vomiting, and flatulence. Abnormalities of hepatic, renal and haematological function have been observed during fluconazole therapy in some patients, particularly those with serious underlying diseases such as AIDS and cancer. Other side effects could be headache, rash, vision changes, taste perversion, fatigue and malaise.